Harri Niinikoski profile picture
Harri
Niinikoski
Professor, Institute of Biomedicine
Professor, Nutrition in Medicine (Institute of Biomedicine)

Contact

Areas of expertise

Childhood endocrinology and nutrition
inherited metabolic diseases
neonatal screening
prevention of cardiovascular risk factors.

Biography

Professor Harri Niinikoski graduated from the Medical School at the University of Turku in 1991, where he also specialized in Pediatrics in 2000 and received subspecialty in Pediatric Endocrinology in 2006. He defended his thesis on prevention of cardiovascular risk factors in childhood in 1997 (The STRIP study). He did his post-doc training at the Childhood Nutrition Research Center at the Baylor School of Medicine, Houston, Texas, in 2001-2003. Subsequently, he worked as a Senior Clinical Researcher and Clinical Lecturer at the Department of Pediatrics, University of Turku, and in 2011-2015 as the Head of the Division of Pediatric Care in Turku University Hospital. From 2015, he has been Professor of Nutrition in Medicine


Teaching

In 2006-2010, Harri Niinikoski worked as a full-time teacher of pediatrics at the Department of Pediatrics, University of Turku.


Research

Professor Harri Niinikoski’s research interest focus on primary prevention of cardiovascular disease, and childhood nutrition, endocrinology and metabolism. Moreover, he has been closely involved in launching the neonatal metabolic screening program which started in Finland in 2015.

Main research projects are 1) The STRIP study (The Special Turku coronary risk factor Intervention Project) which started in 1990 and involved 1062 infants which were randomized into nutrition an intervention or a control group. He is deputy P.I. in STRIP; 2) DIARA2 study which involves 317 children (217 in Turku, 100 in Oulu) whose mothers were treated with either metformin or insulin due to gestational diabetes. The children are now thoroughly investigated at 9 years of age; 3) LPI study. Lysinuric protein intolerance (LPI) is a rare metabolic disease which belongs to the Finnish disease heritage. There are approx. 50 Finnish patients who are annually studied at the Turku University Hospital pediatric metabolic outpatient clinic; 4) Congenital hypothyroidism study. CH has been screened in Finland since 1980, affects 1:2000 newborns and is treated with thyroxine. The outcome of the treatment of CH is investigated in national CH study which is launched in 2018.


Publications

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Association of Physical Activity with Metabolic Profile from Adolescence to Adulthood (2022)

Scandinavian Journal of Medicine and Science in Sports
Lehtovirta Miia, Wu Feitong Rovio Suvi P, Heinonen Olli J, Laitinen TomiT, Niinikoski Harri, Lagström Hanna, Viikari Jorma SA, Rönnemaa Tapani, Jula Antti, Ala-Korpela Mika, Raitakari Olli T, Pahkala Katja
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids (2022)

American Journal of Human Genetics
Ramdas Shweta, Judd Jonathan, Graham Sarah E., Kanoni Stavroula, Wang Yuxuan, Surakka Ida, Wenz Brandon, Clarke Shoa L., Chesi Alessandra, Wells Andrew, Bhatti Konain Fatima, Vedantam Sailaja, Winkler Thomas W., Locke Adam E., Marouli Eirini, Zajac Greg J.M., Wu Kuan-Han H., Ntalla Ioanna, Hui Qin, Klarin Derek, Hilliard Austin T., Wang Zeyuan, Xue Chao, Thorleifsson Gudmar, Helgadottir Anna, Gudbjartsson Daniel F., Holm Hilma, Olafsson Isleifur, Hwang Mi Yeong, Han Sohee, Akiyama Masato, Sakaue Saori, Terao Chikashi, Kanai Masahiro, Zhou Wei, Brumpton Ben M., Rasheed Humaira, Havulinna Aki S., Veturi Yogasudha, Pacheco Jennifer Allen, Rosenthal Elisabeth A., Lingren Todd, QiPing Feng, Kullo Iftikhar J., Narita Akira, Takayama Jun, Martin Hilary C., Hunt Karen A., Trivedi Bhavi, Haessler Jeffrey, Giulianini Franco, Bradford Yuki, Miller Jason E., Campbell Archie, Lin Kuang, Millwood Iona Y., Rasheed Asif, Hindy George, Faul Jessica D., hao WeiZ, Weir David R., Turman Constance, Huang Hongyan, Graff Mariaelisa, Choudhury Ananyo, Sengupta Dhriti, Mahajan Anubha, Brown Michael R., Zhang Weihua, Yu Ketian, Schmidt Ellen M., Pandit Anita, Gustafsson Stefan, Yin Xianyong, Luan Jian’an, Zhao Jing-Hua, Matsuda Fumihiko, Jang Hye-Mi, Yoon Kyungheon, Medina-Gomez Carolina, Pitsillides Achilleas, Hottenga Jouke Jan, Wood Andrew R., Ji Yingji, Gao Zishan, Haworth Simon, Mitchell Ruth E., Chai Jin Fang, Aadahl Mette, Bjerregaard Anne A., Yao Jie, Manichaikul Ani, Lee Wen-Jane, Hsiung Chao Agnes, Warren Helen R., Ramirez Julia, Bork-Jensen Jette, Kårhus Line L., Goel Anuj, Sabater-Lleal Maria, Noordam Raymond, Mauro Pala, Matteo Floris, McDaid Aaron F., Marques-Vidal Pedro, Wielscher Matthias, Trompet Stella, Sattar Naveed, Møllehave Line T., Munz Matthias, Zeng Lingyao, Huang Jianfeng, Yang Bin, Poveda Alaitz, Kurbasic Azra, Schönherr Sebastian, Forer Lukas, Scholz Markus, Galesloot Tessel E., Bradfield Jonathan P., Ruotsalainen Sanni E., Daw E. Warwick, Zmuda Joseph M., Mitchell Jonathan S., Fuchsberger Christian, Christensen Henry, Brody Jennifer A., Le Phuong, Feitosa Mary F., Wojczynski Mary K., Hemerich Daiane, Preuss Michael, Mangino Massimo, Christofidou Paraskevi, Verweij Niek, Benjamins Jan W., Engmann Jorgen, Noah Tsao L., Verma Anurag, Slieker Roderick C., Lo Ken Sin, Zilhao Nuno R., Kleber Marcus E., Delgado Graciela E., Huo Shaofeng, Ikeda Daisuke D., Iha Hiroyuki, Yang Jian, Liu Jun, Demirkan Ayşe, Leonard Hampton L., Marten Jonathan, Emmel Carina, Schmidt Börge, Smyth Laura J., Cañadas-Garre Marisa, Wang Chaolong, Nakatochi Masahiro, Wong Andrew, Hutri-Kähönen Nina, Sim Xueling, Xia Rui, Huerta-Chagoya Alicia, Fernandez-Lopez Juan Carlos, Lyssenko Valeriya, Nongmaithem Suraj S., Sankareswaran Alagu, Irvin Marguerite R., Oldmeadow Christopher, Kim Han-Na, Ryu Seungho, Timmers Paul R.H.J., Arbeeva Liubov, Dorajoo Rajkumar, Lange Leslie A., Prasad Gauri, Lorés-Motta Laura, Pauper Marc, Long Jirong, Li Xiaohui, Theusch Elizabeth, Takeuchi Fumihiko, Spracklen Cassandra N., Loukola Anu, Bollepalli Sailalitha, Warner Sophie C., Wang Ya Xing, Wei Wen B., Nutile Teresa, Ruggiero Daniela, Sung Yun Ju, Chen Shufeng, Liu Fangchao, Yang Jingyun, Kentistou Katherine A., Banas Bernhard, Morgan Anna, Meidtner Karina, Bielak Lawrence F., Smith Jennifer A., Hebbar Prashantha, Farmaki Aliki-Eleni, Hofer Edith, Lin Maoxuan, Concas Maria Pina, Vaccargiu Simona, van der Most Peter J. , Pitkänen Niina, Cade Brian E., van der Laan Sander W., Chitrala Kumaraswamy Naidu, Weiss Stefan, Bentley Amy R., Doumatey Ayo P., Adeyemo Adebowale A., Lee Jong Young, Petersen Eva R.B., Nielsen Aneta A., Choi Hyeok Sun, Nethander Maria, Freitag-Wolf Sandra, Southam Lorraine, Rayner Nigel W., Wang Carol A., Lin Shih-Yi, Wang Jun-Sing, Couture Christian, Lyytikäinen Leo-Pekka, Nikus Kjell, Cuellar-Partida Gabriel, Vestergaard Henrik, Hidalgo Bertha, Giannakopoulou Olga, Cai Qiuyin, Obura Morgan O., van Setten Jessica, He Karen Y., Tang Hua, Terzikhan Natalie, Shin Jae Hun, Jackson Rebecca D., Reiner Alexander P., Martin Lisa Warsinger, Chen Zhengming, Li Liming, Kawaguchi Takahisa, Thiery Joachim, Bis Joshua C., Launer Lenore J., Li Huaixing, Nalls Mike A., Raitakari Olli T., Ichihara Sahoko, Wild Sarah H., Nelson Christopher P., Campbell Harry, Jäger Susanne, Nabika Toru, Al-Mulla Fahd, Niinikoski Harri, Braund Peter S., Kolcic Ivana, Kovacs Peter, Giardoglou Tota, Katsuya Tomohiro, de Kleijn Dominique, de Borst Gert J., Kim Eung Kweon, Adams Hieab H.H., Ikram M. Arfan, Zhu Xiaofeng, Asselbergs Folkert W., Kraaijeveld Adriaan O., Beulens Joline W.J., Shu Xiao-Ou, Rallidis Loukianos S., Pedersen Oluf, Hansen Torben, Mitchell Paul, Hewitt Alex W., Kähönen Mika, Pérusse Louis, Bouchard Claude, Tönjes Anke, Ida Chen Yii-Der, Pennell Craig E., Mori Trevor A., Lieb Wolfgang, Franke Andre, Ohlsson Claes, Mellström Dan, Cho Yoon Shin, Lee Hyejin, Yuan Jian-Min, Koh Woon-Puay, Rhee Sang Youl, Woo Jeong-Taek, Heid Iris M., Stark Klaus J., Zimmermann Martina E., Völzke Henry, Homuth Georg, Evans Michele K., Zonderman Alan B., Polasek Ozren, Pasterkamp Gerard, Hoefer Imo E., Redline Susan, Pahkala Katja, Oldehinkel Albertine J., Snieder Harold, Biino Ginevra, Schmidt Reinhold, Schmidt Helena, Bandinelli Stefania, Dedoussis George, Thanaraj Thangavel Alphonse , Peyser Patricia A., Kato Norihiro, Schulze Matthias B., Girotto Giorgia, Böger Carsten A., Jung Bettina, Joshi Peter K., Bennett David A., De Jager Philip L., Lu Xiangfeng, Mamakou Vasiliki, Brown Morris, Caulfield Mark J., Munroe Patricia B., Guo Xiuqing, Ciullo Marina, Jonas Jost B., Samani Nilesh J., Kaprio Jaakko, Pajukanta Päivi, Tusié-Luna Teresa, Aguilar-Salinas Carlos A., Adair Linda S., Bechayda Sonny Augustin, Silva H. Janakade, Wickremasinghe Ananda R., Krauss Ronald M., Wu Jer-Yuarn, Zheng Wei, den Hollander Anneke I., Bharadwaj Dwaipayan, Correa Adolfo, Wilson James G., Lind Lars, Heng Chew-Kiat, Nelson Amanda E., Golightly Yvonne M., Wilson James F., Penninx Brenda, Kim Hyung-Lae, Attia John, Scott Rodney J., Rao D.C., Arnett Donna K., Walker Mark, Scott Laura J., Koistinen Heikki A., Chandak Giriraj R., Mercader Josep M., Villalpando Clicerio Gonzalez, Orozco Lorena, Fornage Myriam, Tai E. Shyong, van Dam Rob M., Lehtimäki Terho, Chaturvedi Nish, Yokota Mitsuhiro, Liu Jianjun, Reilly Dermot F., McKnight Amy Jayne, Kee Frank, Jöckel Karl-Heinz, McCarthy Mark I., Palmer Colin N.A., Vitart Veronique, Hayward Caroline, Simonsick Eleanor, van Duijn Cornelia M., Jin Zi-Bing, Lu Fan, Hishigaki Haretsugu, Lin Xu, März Winfried, Gudnason Vilmundur, Tardif Jean-Claude, Lettre Guillaume, t Hart Leen M., Elders Petra J.M., Rader Daniel J., Damrauer Scott M., Kumari Meena, Kivimaki Mika, van der Harst Pim, Spector Tim D., Loos Ruth J.F., Province Michael A., Parra Esteban J., Cruz Miguel, Psaty Bruce M., Brandslund Ivan, Pramstaller Peter P., Rotimi Charles N., Christensen Kaare, Ripatti Samuli, Widén Elisabeth, Hakonarson Hakon, Grant Struan F.A., Kiemeney Lambertus, de Graaf Jacqueline, Loeffler Markus, Kronenberg Florian, Gu Dongfeng, Erdmann Jeanette, Schunkert Heribert, Franks Paul W., Linneberg Allan, Jukema J. Wouter, Khera Amit V., Männikkö Minna, Jarvelin Marjo-Riitta, Kutalik Zoltan, Francesco Cucca, Mook-Kanamori Dennis O., van Dijk Ko Willems, Watkins Hugh, Strachan David P., Grarup Niels, Sever Peter, Poulter Neil, Huey-Herng Sheu Wayne, Rotter Jerome I., Dantoft Thomas M., Karpe Fredrik, Neville Matt J., Timpson Nicholas J., Cheng Ching-Yu, Wong Tien-Yin, Khor Chiea Chuen, Li Hengtong, Sabanayagam Charumathi, Peters Annette, Gieger Christian, Hattersley Andrew T., Pedersen Nancy L., Magnusson Patrik K.E., Boomsma Dorret I., de Geus Eco J.C., Cupples L. Adrienne, van Meurs Joyce B.J., Ikram Arfan, Ghanbari Mohsen, Gordon-Larsen Penny, Huang Wei, Kim Young Jin, Tabara Yasuharu, Wareham Nicholas J., Langenberg Claudia, Zeggini Eleftheria, Tuomilehto Jaakko, Kuusisto Johanna, Laakso Markku, Ingelsson Erik, Abecasis Goncalo, Chambers John C., Kooner Jaspal S., de Vries Paul S., Morrison Alanna C., Hazelhurst Scott, Ramsay Michèle, North Kari E., Daviglus Martha, Kraft Peter, Martin Nicholas G., Whitfield John B., Abbas Shahid, Saleheen Danish, Walters Robin G., Holmes Michael V., Black Corri, Smith Blair H., Baras Aris, Justice Anne E., Buring Julie E., Ridker Paul M., Chasman Daniel I., Kooperberg Charles, Tamiya Gen, Yamamoto Masayuki, van Heel David A., Trembath Richard C., Wei Wei-Qi, Jarvik Gail P., Namjou Bahram, Hayes M. Geoffrey, Ritchie Marylyn D., Jousilahti Pekka, Salomaa Veikko, Hveem Kristian, Åsvold Bjørn Olav, Kubo Michiaki, Kamatani Yoichiro, Okada Yukinori, Murakami Yoshinori, Kim Bong-Jo, Thorsteinsdottir Unnur, Stefansson Kari, Zhang Jifeng, Chen Y. Eugene, Ho Yuk-Lam, Lynch Julie A., Tsao Philip S., Chang Kyong-Mi, Cho Kelly, O'Donnell Christopher J., Gaziano John M., Wilson Peter, Mohlke Karen L., Frayling Timothy M., Hirschhorn Joel N., Kathiresan Sekar, Boehnke Michael, Million Veterans Program, Global Lipids Genetics Consortium, Grant Struan, Natarajan Pradeep, Sun Yan V., Morris Andrew P., Deloukas Panos, Peloso Gina, Assimes Themistocles L., Willer Cristen J., Zhu Xiang, Brown Christopher D.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))