Areas of expertise
PhD Jari Nuutila, University Teacher and independent infection researcher (Current, Department of Biochemistry, University of Turku).
Research topics: Host-Microbe Interactions. Applications of leukocyte cell surface receptor expression and serum soluble markers in distinguishing between febrile bacterial and viral infections. http://www.utu.fi/fi/yksikot/sci/yksikot/biokemia/tutkimus/bk/immunochemistry/Sivut/home.aspx
Academic career: MSc in Biochemistry (Calcium dependence of phagocytosis and respiratory burst activity measured by flow cytometer and luminometer, 1994), PhD in Biochemistry (Interrelations between receptor expression, respiratory burst, and phagocytosis, 2004), Adjunct professor/Docent in Biochemistry (2009, University of Turku) and Immunology (2013, University of Helsinki)
Publications: 30 scientific publications (27 original and 3 review articles)
The primary goal of this multidisciplinary basic research on innate immunology is to study the expression patterns of several leukocyte cell surface markers and serum soluble markers in infectious/inflammatory diseases and in healthy controls in order to understand how the mechanisms of cellular and humoral innate immunity are regulated.
The novelty of this study compared with the previous studies is that: (A) For the first time ever, such a large panel of potential bacterial infection markers will be quantified simultaneously, and (B) The quantitative analysis of these markers will be determined in authentic in vivo circumstances (in patients with bacterial or viral infections, and in healthy controls).
The second goal of this study is to transform above-mentioned basic research findings into clinical diagnostic applications. The ultimate goal is to find out whether it is possible to produce a novel fast method(s) for distinguishing between bacterial and viral infections in less than 30 minutes.