Juhani
Knuuti
Director, Turku PET Centre
Professor, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes - A positron-emitting tomography study (2005)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Free Fatty Acid Biodistribution and Triglyceride Metabolism Using the Fatty Acid Analogue 18F-FTHA during Fasting and Hyperinsulinemia (2005)
European Journal of Nuclear Medicine and Molecular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Rosiglitazone improves myocardial glucose uptake in patients with type 2 diabetes and coronary artery disease - A 16-week randomized, double-blind, placebo-controlled study (2005)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
The effect of the Ala(12) allele of the peroxisome proliferator-activated receptor-gamma 2 gene on skeletal muscle glucose uptake depends on obesity: A positron emission tomography study (2005)
Journal of Clinical Endocrinology and Metabolism
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Increased lipoprotein(a) is associated with reduced myocardial vasoreactivity in young healthy men (2005)
Atherosclerosis
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Efficacy of ciprofloxacin-releasing bioabsorbable osteoconductive bone defect filter for treatment of experimental osteomyelitis due to Staphylococcus aureus (2005)
Antimicrobial Agents and Chemotherapy
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
The Uptake of F-18-FDG and H-3-PK11195 on Atherosclerotic Plaques in Mice (2005)
European Journal of Nuclear Medicine and Molecular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Rosiglitazone increases the concentration of large, buoyant but not small dense LDL in patients with type 2 diabetes and coronary artery disease, a 16 week randomised, double-blind, placebo-controlled study (2005)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Cardiac function and efficiency are dependent on free fatty acid availibility in patients with idiopathic dilated cardiomyopathy and heart failure (2005)
Circulation
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Imaging of Oxidative Metabolism: Insight into cardiac performance (Marie Curie Lecture) (2005)
European Journal of Nuclear Medicine and Molecular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))