Keyword: Cancer research

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New Research Data on the Regulation of Hormone-dependent Breast Cancer

22.04.2021

Notch proteins are key regulators of growth and differentiation of both normal and cancer cells. Researchers in Turku, Finland, have now demonstrated that the activities of distinct Notch family members are modified differently by phosphorylation. These results can be used in the development of new cancer treatments, especially for hormone-dependent breast cancer. 

Novel Therapy-resistance Mechanism Promoting the Growth of Breast Cancer Brain Metastasis

29.01.2021

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska’s research group at Turku Bioscience observed that SORLA functionally contributes to the most reported therapy-resistant mechanism by which the cell-surface receptor HER3 counteracts HER2 targeting therapy in HER2-positive cancers. Removing SORLA from cancer cells sensitised anti-HER2 resistant breast cancer brain metastasis to targeted therapy.

Rapid Test for Ovarian Cancer Detection Developed at the University of Turku Received an International Innovation Award

02.12.2020

A rapid test for ovarian cancer detection developed at the University of Turku has received the international Rapid Testing Innovation Award. The awarded article is part of the dissertation of Doctoral Candidate Sherif Bayoumy. Next, the cancer diagnostics team of the Biotechnology unit at the Department of Biochemistry aims to expand the research to other cancer types.

Health through Research: Studying Skin with Molecular Precision

10.09.2020

Top-level skin cancer research acknowledging the individuality of cancer is conducted in Turku. In the studies, the characteristics of cancer are examined at the level of tracers and molecules. This opens up the opportunity to tailor the most suitable treatment for each patient. The studies are rewarding for both the researchers and the research subjects. At best, patients with advanced skin cancer benefit from the new medicinal products used in trials long before these products are in commercial use.

Researchers Discovered New Information on the Regulation of Cancer Cell Motility

19.08.2020

PIM kinases are enzymes that promote metastatic growth and spread of cancer cells. Researchers from the University of Turku, Finland, have obtained new information on how the PIM kinases enhance cancer cell motility by regulating the formation of actin fibres in the cytoskeleton. The published results support the development of PIM-targeted therapies to prevent metastasis formation in cancer patients.