Heli Jokela

Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance (2025)

Cell Reports

Lehtonen, Henna; Jokela, Heli; Hofmann, Julian; Tola, Lauriina; Mehmood, Arfa; Ginhoux, Florent; Becher, Burkhard; Greter, Melanie; Yegutkin, Gennady G.; Salmi, Marko; Gerke, Heidi; Rantakari, Pia

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Single-Cell Proteomics Reveals the Defined Heterogeneity of Resident Macrophages in White Adipose Tissue (2021)

Frontiers in Immunology

Félix Inês, Jokela Heli, Karhula Joona, Kotaja Noora, Savontaus Eriika, Salmi Marko, Rantakari Pia

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Fetal-derived macrophages persist and sequentially maturate in ovaries after birth in mice (2020)

European Journal of Immunology

Heli Jokela, Emmi Lokka, Miikka Kiviranta, Sofia Tyystjärvi, Heidi Gerke, Kati Elima, Marko Salmi, Pia Rantakari

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Hydroxysteroid (17β) dehydrogenase 1 expressed by Sertoli cells contributes to steroid synthesis and is required for male fertility (2018)

FASEB Journal

Janne Hakkarainen, Fu-Ping Zhang, Heli Jokela, Artur Mayerhofer, Rüdiger Behr, Sheyla Cisneros-Montalvo, Mirja Nurmio, Jorma Toppari, Claes Ohlsson, Noora Kotaja, Petra Sipilä, and Matti Poutanen

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Outcome of Hsd17b1 gene deletion in ovarian and adipose tissue function : alterations resulting from both HSD17B1 enzyme inhibition and the off-target effect on the Naglu gene (2017)

Jokela Heli

(G5 Artikkeliväitöskirja)

Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage disease (2017)

Scientific Reports

Jokela H, Hakkarainen J, Kätkänaho L, Pakarinen P, Ruohonen ST, Tena-Sempere M, Zhang FP, Poutanen M

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Hydroxysteroid (17b)-dehydrogenase 1–deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone production (2015)

FASEB Journal

Janne Hakkarainen, Heli Jokela, Pirjo Pakarinen, Hanna Heikela, Laura Kätkänaho, Liesbeth Vandenput, Claes Ohlsson, Fu-Ping Zhang, and Matti Poutanen

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

The diversity of sex steroid action: novel functions of hydroxysteroid (17 beta) dehydrogenases as revealed by genetically modified mouse models (2012)

Journal of Endocrinology

Saloniemi T, Jokela H, Strauss L, Pakarinen P, Poutanen M

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice (2010)

Human Molecular Genetics

Rantakari P, Nikkilä J, Jokela H, Ola R, Pylkäs K, Lagerbohm H, Sainio K, Poutanen M, Winqvist R

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos (2010)

Endocrinology

Jokela H, Rantakari P, Lamminen T, Strauss L, Ola R, Mutka AL, Gylling H, Miettinen T, Pakarinen P, Sainio K, Poutanen M

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Heli

Jokela

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Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance (2025)

Single-Cell Proteomics Reveals the Defined Heterogeneity of Resident Macrophages in White Adipose Tissue (2021)

Fetal-derived macrophages persist and sequentially maturate in ovaries after birth in mice (2020)

Hydroxysteroid (17β) dehydrogenase 1 expressed by Sertoli cells contributes to steroid synthesis and is required for male fertility (2018)

Outcome of Hsd17b1 gene deletion in ovarian and adipose tissue function : alterations resulting from both HSD17B1 enzyme inhibition and the off-target effect on the Naglu gene (2017)

Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage disease (2017)

Hydroxysteroid (17b)-dehydrogenase 1–deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone production (2015)

The diversity of sex steroid action: novel functions of hydroxysteroid (17 beta) dehydrogenases as revealed by genetically modified mouse models (2012)

Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice (2010)

Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos (2010)