Jukka Westermarck

CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling (2020)

iScience

Mohd Moin Khan, Ubaid Ullah, Meraj H. Khan, Lingjia Kong, Robert Moulder, Tommi Välikangas, Santosh Dilip Bhosale, Elina Komsi, Omid Rasool, Zhi Chen, Laura L. Elo, Jukka Westermarck, Riitta Lahesmaa

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma (2020)

Brain Communications

Merisaari J, Denisova OV, Doroszko M, Le Joncour V, Johansson P, Leenders WPJ, Kastrinsky DB, Zaware N, Narla G, Laakkonen P, Nelander S, Ohlmeyer M, Westermarck J

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors (2020)

Oncogene

O’Connor C., Leonard D., Wiredja D., Avelar R., Wang Z., Schlatzer D., Bryson B., Tokala E., Taylor S., Upadhyay A., Sangodkar J., Gingras A., Westermarck J., Xu W., DiFeo A., Brautigan D., Haider S., Jackson M., Narla G., Narla G.

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1 (2020)

Journal of Biological Chemistry

Kauko O, Imanishi SY, Kulesskiy E, Yetukuri L, Laajala TD, Sharma M, Pavic K, Aakula A, Rupp C, Jumppanen M, Haapaniemi P, Ruan L, Yadav B, Suni V, Varila T, Reimand J, Corthals GL, Aittokallio T, Wennerberg K, Westermarck J

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis (2020)

Cancer Research

Qiao X, Liu Y, Prada ML, Mohan AK, Gupta A, Jaiswal A, Sharma M, Merisaari J, Haikala HM, Talvinen K, Yetukuri L, Pylvänäinen JW, Klefstrom J, Kronqvist P, Meinander A, Aittokallio T, Hietakangas V, Eilers M, Westermarck J, Westermarck J

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Good guy in bad company: How STRNs convert PP2A into an oncoprotein (2020)

Cancer Cell

Kari J Kurppa, Jukka Westermarck

(B1 Kirjoitus tieteellisessä aikakauslehdessä)

Protein interactome of the Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Th17 cells (2020)

Current Research in Immunology

Khan MM, Välikangas T, Khan MH, Moulder R, Ullah U, Bhosale S, Komsi E, Butt U, Qiao X, Westermarck J, Elo LL, Lahesmaa R

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

(2S, 4R)-4-[18F]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models (2020)

Molecular Imaging and Biology

Maxwell WG Miner, Heidi Liljenbäck, Jenni Virta, Joni Merisaari, Vesa Oikonen, Jukka Westermarck, Xiang-Guo Li, Anne Roivainen

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Piecing Together a Broken Tumor Suppressor Phosphatase for Cancer Therapy (2020)

Cell

Westermarck J, Neel BG

(B1 Kirjoitus tieteellisessä aikakauslehdessä)

Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models (2020)

Neurotherapeutics

Wei H, Zhang HL, Wang XC, Xie JZ, An DD, Wan L, Wang JZ, Zeng Y, Shu XJ, Westermarck J, Lu YM, Ohlmeyer M, Liu R

(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

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CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling (2020)

Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma (2020)

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors (2020)

Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1 (2020)

UBR5 Is Coamplified with MYC in Breast Tumors and Encodes an Ubiquitin Ligase That Limits MYC-Dependent Apoptosis (2020)

Good guy in bad company: How STRNs convert PP2A into an oncoprotein (2020)

Protein interactome of the Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Th17 cells (2020)

(2S, 4R)-4-[18F]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models (2020)

Piecing Together a Broken Tumor Suppressor Phosphatase for Cancer Therapy (2020)

Direct Activation of Protein Phosphatase 2A (PP2A) by Tricyclic Sulfonamides Ameliorates Alzheimer's Disease Pathogenesis in Cell and Animal Models (2020)