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A Novel Folic Acid Linked Drug Has Shown to Attenuate Inflammation and Disease Activity in Animal Model of Multiple Sclerosis

01.02.2021

Recently published research has indicated that folate receptor targeting therapy constrains inflammation in inflammatory demyelinating central nervous system lesions and may inhibit progression of the disease in animal model of multiple sclerosis (MS). This research has been conducted in co-operation with Turku PET Centre, Purdue University and Endocyte Inc (now part of Novartis Institutes for BioMedical Research, NIBR).

Scientists Believe Studies by Colleagues Are More Prone to Biases than Their Own Studies

03.02.2021

The properties of human mind affect the quality of scientific knowledge through the insertion of unconscious cognitive biases. Scientists from the University of Turku, Finland, have found that the current level of awareness about research biases is generally low among ecology scientists. Underestimation of the risks associated with unconscious cognitive biases prevents avoiding these risks in a scientist’s own research. Due to unconscious origin of biases, it is impossible to combat them without external intervention.

Novel Therapy-resistance Mechanism Promoting the Growth of Breast Cancer Brain Metastasis

29.01.2021

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska’s research group at Turku Bioscience observed that SORLA functionally contributes to the most reported therapy-resistant mechanism by which the cell-surface receptor HER3 counteracts HER2 targeting therapy in HER2-positive cancers. Removing SORLA from cancer cells sensitised anti-HER2 resistant breast cancer brain metastasis to targeted therapy.

BalticSatApps Successfully Paving Way for Earth Observation-based Innovations in Baltic Sea Region

12.01.2021

The European Copernicus Programme provides Earth Observation (EO) data free of charge on an open-access basis. The Copernicus services are based on satellite and in situ observations, and cater to even near real-time data needs. The services provide global data which can also be used for local and regional needs. The data can, for example, help to make visible different phenomena affecting Earth, such as climate change and urban development.

Imaging the Twilight Zone − General anesthesia and normal sleep affect brain in an amazingly similar way as consciousness fades

28.12.2020

What happens in the brain when our conscious awareness of the surrounding world and of ourselves fades during general anesthesia and normal sleep? This fundamental question was studied with novel experimental designs and functional brain imaging by Finnish scientists. They succeeded in separating the specific changes related to consciousness from the more widespread overall effects, commonly misinterpreted as the neural correlates of consciousness. The effects of anesthesia and sleep on brain activity turned out to be surprisingly similar.