Väitös (kariologia ja korjaava hammashoito): MSc Omar Abdelaziz Ismail
MSc Omar Abdelaziz Ismail esittää väitöskirjansa ”Clinical and laboratory evaluation of dimethyl sulfoxide dentin pretreatments” julkisesti tarkastettavaksi Turun yliopistossa perjantaina 17.4.2026 klo 12.00 (Turun yliopisto, Dentalia, Arje Scheinin -sali, Lemminkäisenkatu 2, Turku).
Vastaväittäjänä toimii professori Lezize Sebnem Türkün (Ege University, İzmir, Turkki) ja kustoksena professori Arzu Tezvergil-Mutluay (Turun yliopisto). Tilaisuus on englanninkielinen. Väitöksen alana on kariologia ja korjaava hammashoito.
Tiivistelmä väitöstutkimuksesta:
When we get a filling at the dentist, we expect it to stay in place and look natural for a long time. However, the "glue" that holds the filling to the tooth is often the weakest link. Over time, moisture and natural enzymes in the mouth can break down this bond, causing the filling to leak, stain, or fall out. My research focused on using a simple liquid called dimethyl sulfoxide (DMSO) as a pretreatment to make these dental bonds much more durable.
Key Findings of the Research
• Stronger and Longer-Lasting Bonds: In laboratory tests, treating the tooth with DMSO helped the dental glue penetrate deeper and more evenly. This created a much stronger connection that didn't weaken over time like traditional methods often do.
• Success in Real Patients: This research followed real patients for three years to see how their fillings performed. The results were clear: for specific types of cavities, 89% of the fillings treated with DMSO were still successful after three years, compared to only 65% of the fillings done with the standard method.
• Less Pain and Better Appearance: Patients who received the DMSO treatment reported significantly less tooth sensitivity immediately after the procedure. Additionally, their fillings had less staining around the edges, keeping them looking clean and natural for longer.
New Information Provided by This Research
Before this study, we knew that bonding to teeth was a "sensitive" process, if the tooth was slightly too dry, the glue might not stick well. This research provides the new discovery that DMSO makes the bonding process much more reliable, allowing the glue to work effectively even on dry tooth surfaces.
Furthermore, while earlier studies were mostly done in labs, this research provides the first long-term evidence from real clinical trials that this technique significantly improves the lifespan of fillings in actual patients.
Impact on the Surrounding World
The most significant impact of this research is that it offers a practical, low-cost way to make dental work last longer. For patients, this means fewer repeat visits to the dentist to fix or replace old fillings, which saves both time and money. It also leads to less physical discomfort, as fillings are less likely to cause sensitivity.
For the dental profession, it provides a more "forgiving" technique. Because the bonding process becomes less sensitive to moisture levels, dentists can achieve high-quality, consistent results more easily. Since DMSO is already widely used in medicine and is very easy to apply, it is a tool that can be immediately adopted with the right concentration in daily dental practice to improve oral health outcomes for everyone.
